882403-69-2
882403-69-2
Chemical Structure
Malonganenone A
- CAS No.: 882403-69-2
- Formula:C26H38N4O2
- Molecular Weight:438.61
IUPAC Name: 3-methyl-7-((2E,6E,11Z)-3,7,11,15-tetramethyl-13-oxohexadeca-2,6,11-trien-1-yl)-3,7-dihydro-6H-purin-6-one
InChIKey: YFUQCEYIDJYEII-HLMZKVHVSA-N
SMILES: O=C1N=CN(C)C2=C1N(C/C=C(C)/CC/C=C(C)/CCC/C(C)=C\C(CC(C)C)=O)C=N2
Biological Activity: Malonganenone A is an antimalarial marine alkaloid that disrupts the interaction between PfHsp70-x and Hsp40. Malonganenone A inhibits plasmodial and not human Hsp70 ATPase activity (Hsp40-stimulated), and hindered the aggregation suppression activity of PfHsp70-x[1].
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Malonganenone A | Malonganenone A is an antimalarial marine alkaloid that disrupts the interaction between PfHsp70-x and Hsp40. Malonganenone A inhibits plasmodial and not human Hsp70 ATPase activity (Hsp40-stimulated), and hindered the aggregation suppression activity of PfHsp70-x. | |||||||||||||||||||||
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