Axl Inhibitor
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Axl-IN-3
0 ImagesCat. No.: HY-144706CAS No.: 2783991-34-2Axl-IN-3 is a potent, selective and orally active AXL kinase inhibitor with an IC50 of 41.5 nM. Axl-IN-3 has lower inhibition of other kinases.
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R916562
0 ImagesCat. No.: HY-104075CAS No.: 1037798-41-6R916562 is an orally active and selective Axl/VEGF-R2 inhibitor with IC50s of 136 nM and 24 nM, respectively. R916562 has anti-angiogenesis and anti-metastasis.
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AXL-IN-14
0 ImagesCat. No.: HY-152075CAS No.: 2947506-65-0AXL-IN-14 is a potent and orally active AXL inhibitor with an IC50 value of 0.8 nM. AXL-IN-14 inhibits Gas6/AXL-mediated cell migration and invasion. AXL-IN-14 decreases the expression of p-AXL and p-AKT proteins. AXL-IN-14 shows anti-tumor activity.
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Axl-IN-5
0 ImagesCat. No.: HY-146596CAS No.: 2642224-24-4Axl-IN-5 (compound 1) is a AXL inhibitor with an IC50 of 283 nM. Axl-IN-5 has anticancer effects.
