1037798-41-6
1037798-41-6
Chemical Structure
R916562
- CAS No.: 1037798-41-6
- Formula:C26H30ClN9S
- Molecular Weight:536.09
IUPAC Name: N3-(4-(4-((1R,2R,4S)-bicyclo[2.2.1]heptan-2-yl)piperazin-1-yl)phenyl)-1-(2-chloro-7-methylthieno[3,2-d]pyrimidin-4-yl)-1H-1,2,4-triazole-3,5-diamine
InChIKey: HLRDOMFIYHUBLJ-SQGPQFPESA-N
SMILES: NC1=NC(NC(C=C2)=CC=C2N3CCN([C@H]4[C@@H]5CC[C@@H](C5)C4)CC3)=NN1C6=NC(Cl)=NC7=C6SC=C7C
Biological Activity: R916562 is an orally active and selective Axl/VEGF-R2 inhibitor with IC50s of 136 nM and 24 nM, respectively. R916562 has anti-angiogenesis and anti-metastasis[1].
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R916562 | R916562 is an orally active and selective Axl/VEGF-R2 inhibitor with IC50s of 136 nM and 24 nM, respectively. R916562 has anti-angiogenesis and anti-metastasis. | |||||||||||||||||||||
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References
Keywords
