2783991-34-2
2783991-34-2
Chemical Structure
Axl-IN-3
- CAS No.: 2783991-34-2
- Formula:C24H25ClN6O2
- Molecular Weight:464.95
IUPAC Name: (R)-6-chloro-3-(1-(4-methoxyphenyl)-1H-pyrazol-4-yl)-N-(1-(oxetan-3-yl)pyrrolidin-3-yl)-1H-indazol-5-amine
InChIKey: HXMXYFUYRVGKEH-MRXNPFEDSA-N
SMILES: COC1=CC=C(C=C1)N2C=C(C=N2)C3=NNC4=C3C=C(C(Cl)=C4)N[C@@H]5CCN(C5)C6COC6
Biological Activity: Axl-IN-3 is a potent, selective and orally active AXL kinase inhibitor with an IC50 of 41.5 nM. Axl-IN-3 has lower inhibition of other kinases[1].
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Axl-IN-3 | Axl-IN-3 is a potent, selective and orally active AXL kinase inhibitor with an IC50 of 41.5 nM. Axl-IN-3 has lower inhibition of other kinases. | |||||||||||||||||||||
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