Trk Receptor
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Trk Receptor Inhibitors
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Trk Receptor Agonists
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Trk Receptor Antagonists
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Trk Receptor Activators
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Trk Receptor Modulators
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Trk Receptor Degraders
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Trk Receptor Control
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Trk Receptor Related Products (116)
Related Products (116)
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Phenylmethyl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside
0 ImagesCat. No.: HY-N15532CAS No.: 88510-11-6Phenylmethyl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside (Compound 12) is a nerve growth factor (NGF) secretion promoter, which is found in plants of the genus Piper. Phenylmethyl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside is promising for research of neurodegenerative diseases (such as Parkinson's disease and Alzheimer's disease) and diabetic polyneuropathy.
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TRKB(NTRK2) Recombinant Human Active Protein Kinase
0 ImagesCat. No.: HY-E70870TRKB(NTRK2) is a member of tyrosine kinase gene family. TRKB is the primary receptor for brain-derived nerve growth factor (BDNF) and neurotrophin 4/5 (NT4/5). TRKB(NTRK2) Recombinant Human Active Protein Kinase is a recombinant TRKB(NTRK2) protein that can be used to study TRKB(NTRK2)-related functions.
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TRK-IN-16
0 ImagesCat. No.: HY-146522CAS No.: 1365212-81-2TRK-IN-16 is a potent inhibitor of TRK. Protein kinases play a critical role in the control of cell growth and differentiation and are responsible for the control of a wide variety of cellular signal transduction processes. TRK-IN-16 has the potential for the research of TRK-related diseases (extracted from patent WO2012034091A1, compound X-21).
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TRK-IN-26
0 ImagesCat. No.: HY-160166CAS No.: 2412309-52-3
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RET/TRKA-IN-1
0 ImagesCat. No.: HY-161775CAS No.: 3048634-52-9
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(3S,4R)-PF-6683324
0 ImagesCat. No.: HY-112436ACAS No.: 1799789-00-6
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TRK-IN-14
0 ImagesCat. No.: HY-146519CAS No.: 1365212-84-5TRK-IN-14 is a potent inhibitor of TRK. Protein kinases play a critical role in the control of cell growth and differentiation and are responsible for the control of a wide variety of cellular signal transduction processes. TRK-IN-14 has the potential for the research of TRK-related diseases (extracted from patent WO2012034091A1, compound X-47).
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IGF-1R modulator 1
0 ImagesCat. No.: HY-402309CAS No.: 2375424-89-6IGF-1R modulator 1 (Example 5) is an IGF-1R modulator, with EC50s of 0.29 μM (FGFR1), 0.25 μM (IGF1R), 0.34 μM (TrkA), 0.39 μM (TrkB). IGF-1R modulator 1 can be used for research of diseases characterised by impaired signalling of neurotrophins and/or other trophic factors, such as Alzheimer's disease.
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Protein kinase inhibitor 4
0 ImagesCat. No.: HY-153743CAS No.: 2278205-04-0Protein kinase inhibitor 4 (Compound 3) is a protein kinase inhibitor that inhibits TRK-A and ROS1 (IC50=3.0 nM and 104 nM respectively).
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hTrkA-IN-2
0 ImagesCat. No.: HY-139871CAS No.: 2986533-14-4hTrkA-IN-2 is a selective hTrkA allosteric inhibitor with an IC50 value of 3.9 nM.
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TRK-IN-28
0 ImagesCat. No.: HY-163366CAS No.: 2991504-43-7TRK-IN-28 (compound 30f) is a TRK inhibitor with the IC50 values of 0.55 nM, 25.1 nM and 5.4 nM against TRKWT, TRKG595R and TRKG667C, respectively. TRK-IN-2 shows antiproliferative activity with IC50 values of 9.5, 3.7, 205.0 and 48.3 nM against Ba/F3-ETV6-TRKAWT, Ba/F3-ETV6-TRKBWT, Ba/F3-LMNA-TRKG595R and Ba/F3-LMNA-TRKAG667C, respectively.
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Sovutrecdeg
0 ImagesCat. No.: HY-187906CAS No.: 2412058-69-4Sovutrecdeg is a tropomyosin receptor kinase (TRK) degrader with antitumor activity. Sovutrecdeg can be used in tumor-related research.
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TRKA(NTRK1) Recombinant Human Active Protein Kinase
0 ImagesCat. No.: HY-E70869TRKA (also named NTRK1) is a potential new member of the tyrosine kinase gene family. TRKA is a receptor tyrosine kinase that is phosphorylated in response to NGF. A single transmembrane domain divides TRKA into an extracellular domain, important for NGF binding, and an intracellular tyrosine kinase domain, important for signal transduction. TRKA(NTRK1) Recombinant Human Active Protein Kinase is a recombinant TRKA(NTRK1) protein that can be used to study TRKA(NTRK1)-related functions.
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Anti-TrkC Antibody
0 ImagesCat. No.: HY-P992308
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TRK-IN-13
0 ImagesCat. No.: HY-146518CAS No.: 1365221-52-8TRK-IN-13 is a potent inhibitor of TRK. Protein kinases play a critical role in the control of cell growth and differentiation and are responsible for the control of a wide variety of cellular signal transduction processes. TRK-IN-13 has the potential for the research of TRK-related diseases (extracted from patent WO2012034091A1, compound X-24).
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Pan-Trk-IN-2
0 ImagesCat. No.: HY-144028CAS No.: 2583778-77-0Compound cpd-1 is a small molecule Trks inhibitor with good antitumor activity.
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MEDI-1912
0 ImagesCat. No.: HY-P991323MEDI-1912 is a human monoclonal antibody (mAb) targeting NGF/bNGF. MEDI-1912 inhibits signaling through TrkA and p75 receptors. MEDI-1912 can be used in chronic pain research.
