RET/TRKA-IN-1
RET/TRKA-IN-1 (Compound 13) is a dual inhibitor for RET (IC50=0.375 µM) and TRKA. RET/TRKA-IN-1 inhibits cell viability of LC-2 and KM12, with GI50 of 0.72 and 0.25 μM. RET/TRKA-IN-1 arrests the cell cycle at G1 phase.
For research use only. We do not sell to patients.
- CAS No.: 3048634-52-9
- Formula: C30H31N9O
- Molecular Weight:533.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 0.375 µM (RET)
Chemical Information
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CAS No. 3048634-52-9
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Molecular Weight 533.63
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Formula C30H31N9O
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SMILES
CN1N=CC(C2=CC=C(C3=C(NC4=CC=C(CC(NC5=CC(C(C)(C)C)=NN5C)=O)C=C4)N=CN=C3N6)C6=C2)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RET/TRKA-IN-1 Related Classifications
HY-161775 Related Classifications
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