1. Neuronal Signaling Protein Tyrosine Kinase/RTK
  2. Trk Receptor
  3. TRK-IN-14

TRK-IN-14 is a potent inhibitor of TRK. Protein kinases play a critical role in the control of cell growth and differentiation and are responsible for the control of a wide variety of cellular signal transduction processes. TRK-IN-14 has the potential for the research of TRK-related diseases (extracted from patent WO2012034091A1, compound X-47).

For research use only. We do not sell to patients.

TRK-IN-14 Chemical Structure

TRK-IN-14 Chemical Structure

CAS No. : 1365212-84-5

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Description

TRK-IN-14 is a potent inhibitor of TRK. Protein kinases play a critical role in the control of cell growth and differentiation and are responsible for the control of a wide variety of cellular signal transduction processes. TRK-IN-14 has the potential for the research of TRK-related diseases (extracted from patent WO2012034091A1, compound X-47)[1].

Molecular Weight

433.45

Formula

C24H21F2N5O

CAS No.
SMILES

FC(C=C1)=CC=C1CNC(C2=CN=C3N2N=C(N4[C@](C5=CC(F)=CC=C5)([H])CCC4)C=C3)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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TRK-IN-14 Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
TRK-IN-14
Cat. No.:
HY-146519
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