Apolipoprotein
Apolipoprotein Isoform Specific Products
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Apolipoprotein Related Products (86)
Related Products (86)
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Apolipoprotein Isoform Comparison
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PLTP-IN-1
0 ImagesCat. No.: HY-179364CAS No.: 1224565-08-5PLTP-IN-1 (cpd B) is a selective phospholipid transfer protein (PLTP) inhibitor with an IC50 of 1.6 μM. PLTP-IN-1 can block the phospholipid transfer mediated by PLTP and reduce the secretion of apolipoprotein B. PLTP-IN-1 has no effect on the level of triglycerides. PLTP-IN-1 can be used for the research of metabolic disease, such as hyperlipidemia.
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Apoa4 Mouse Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS19408Apoa4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Apoa4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Components
Apoa4 siRNA-1: 5 nmol (HPLC)
Apoa4 siRNA-2: 5 nmol (HPLC)
Apoa4 siRNA-3: 5 nmol (HPLC)
siRNA Negative Control: 5 nmol (HPLC)
FAM-labeled siRNA Negative Control: 5 nmol (HPLC)
GAPDH siRNA Positive Control: 5 nmol (HPLC)
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Terbufibrol (Standard)
0 ImagesCat. No.: HY-101812RCAS No.: 56488-59-6Terbufibrol (Standard) is the analytical standard of Terbufibrol (HY-101812). This product is intended for research and analytical applications. Terbufibrol is an orally active lipid-lowering agent. Terbufibrol inhibits hepatic Cholesterol 7 alpha-hydroxylase. Terbufibrol blocks a step between Acetate and HMG-CoA in the hepatic cholesterol synthesis process. Terbufibrol reduces serum total cholesterol, HDL, LDL, lipoprotein levels, and the cholesterol/phospholipid ratio, with dose- and sex-dependent changes in lipoprotein components. Terbufibrol exerts sustained cholesterol-lowering activity in baboons and rats. Terbufibrol can be used in research related to hypercholesterolemia.
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Apoa2 Mouse Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS19983Apoa2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Apoa2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Components
Apoa2 siRNA-1: 5 nmol (HPLC)
Apoa2 siRNA-2: 5 nmol (HPLC)
Apoa2 siRNA-3: 5 nmol (HPLC)
siRNA Negative Control: 5 nmol (HPLC)
FAM-labeled siRNA Negative Control: 5 nmol (HPLC)
GAPDH siRNA Positive Control: 5 nmol (HPLC)
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EZ-482 (Standard)
0 ImagesCat. No.: HY-103076RCAS No.: 1016456-76-0EZ-482 (Standard) is the analytical standard of EZ-482 (HY-103076). This product is intended for research and analytical applications. EZ-482, a novel ligand of apolipoprotein (apoE), binds to sites on apoE in the C-terminal domain with Kds of 5-10 μM for apoE3 and apoE4. EZ-482 binds to apoE4 by a unique N-terminal allosteric effect. EZ482 has the potential for Alzheimer’s diseas.
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Tisbesiran
0 ImagesCat. No.: HY-185932CAS No.: 2959546-45-1Tisbesiran is an apolipoprotein(a) (apo(a)) synthesis inhibitor. Tisbesiran is a trivalent GalNAc-conjugated double-stranded siRNA with a mixed modification of 2′-OMe/2′-F/P-thio. Its antisense strand targets the KIV-2 repeat region of human apo(a) (LPA) mRNA, thereby inhibiting apolipoprotein(a) synthesis and reducing plasma Lp(a). Tisbesiran can be used for research on Lp(a)-mediated atherosclerotic cardiovascular disease.
