1224565-08-5
1224565-08-5
Chemical Structure
PLTP-IN-1
- CAS No.: 1224565-08-5
- Formula:C27H29FN2O2
- Molecular Weight:432.53
InChIKey: GGFPPOKVLVLXOW-UHFFFAOYSA-N
SMILES: FC1=CC=CC(CN2C3C4=C(C2CN(C3)CC5=CC=C(C(OCC)=C5)OC)C=CC=C4)=C1
Biological Activity: PLTP-IN-1 (cpd B) is a selective phospholipid transfer protein (PLTP) inhibitor with an IC50 of 1.6 μM. PLTP-IN-1 can block the phospholipid transfer mediated by PLTP and reduce the secretion of apolipoprotein B. PLTP-IN-1 has no effect on the level of triglycerides. PLTP-IN-1 can be used for the research of metabolic disease, such as hyperlipidemia[1].
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PLTP-IN-1 | PLTP-IN-1 (cpd B) is a selective phospholipid transfer protein (PLTP) inhibitor with an IC50 of 1.6 μM. PLTP-IN-1 can block the phospholipid transfer mediated by PLTP and reduce the secretion of apolipoprotein B. PLTP-IN-1 has no effect on the level of triglycerides. PLTP-IN-1 can be used for the research of metabolic disease, such as hyperlipidemia. | |||||||||||||||||||||
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References
Keywords
