Tisbesiran

Tisbesiran is an apolipoprotein(a) (apo(a)) synthesis inhibitor. Tisbesiran is a trivalent GalNAc-conjugated double-stranded siRNA with a mixed modification of 2′-OMe/2′-F/P-thio. Its antisense strand targets the KIV-2 repeat region of human apo(a) (LPA) mRNA, thereby inhibiting apolipoprotein(a) synthesis and reducing plasma Lp(a). Tisbesiran can be used for research on Lp(a)-mediated atherosclerotic cardiovascular disease.

For research use only. We do not sell to patients.

  • CAS No.: 2959546-45-1
  • Formula: C500H668F8N165O315P43S8
  • Molecular Weight:15769.92
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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All Apolipoprotein Isoforms

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