2. Signaling Pathways
  3. GPCR/G Protein
  4. Chemerin Receptor
  5. Chemerin Receptor Activator

Chemerin Receptor Activator

Chemerin Receptor Isoform Comparison

Chemerin Receptor Activator (1):

Cat. No. Product Name Effect Purity
  • HY-133159
    Resolvin E2
    		Activator 98.5%
    Resolvin E2 ((-)-Resolvin E2) is an endogenous lipid mediator produced from eicosapentaenoic acid (EPA) under the catalysis of 5-lipoxygenase (5-LOX), and its production increases in hypoxic environments. Resolvin E2 antagonizes BLT1, partially activates ChemR23, and promotes ubiquitin-proteasome-mediated degradation of COX-2. Resolvin E2 reduces the production of prostaglandin E2, blocks polymorphonuclear leukocyte infiltration, and promotes the resolution of airway inflammation. Resolvin E2 ameliorates lipopolysaccharide (LPS) (HY-D1056)-induced depressive-like behaviors. Resolvin E2 can be used in research related to depression, murine peritonitis, neonatal asthma, and other conditions.