Drug Derivative
Drug derivative
Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.
References:
- [1]. Vardanyan RS, et al. Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications. Future Med Chem. 2014 Mar;6(4):385-412.x
- [2]. Ghosh AK, et al. Urea Derivatives in Modern Drug Discovery and Medicinal Chemistry. J Med Chem. 2020 Mar 26;63(6):2751-2788.x
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Drug Derivative Related Products (4032)
Related Products (4032)
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6-Methoxy DiPT hydrochloride
0 Images6-Methoxy DiPT hydrochloride is structurally categorized as a Tryptamine (HY-B2132).
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Xylitan
0 ImagesCat. No.: HY-W007174CAS No.: 491-19-0Xylitan is a derivative of Xylitol (HY-N0538). Xylitan derivatives exhibit in vitro anti-Trypanosoma cruzi activity. Xylitan can be used for the research of Chagas disease.
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Gemin D
0 ImagesCat. No.: HY-N12404CAS No.: 84744-46-7Gemin D is a polyphenolic compound extracted from eucalyptus leaves. Gemin D has cellular antioxidant activity (EC50 = 15.57 μM). Gemin D can be used for research on inflammatory conditions.
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C17 Dihydro ceramide (d18:0/17:0)
0 ImagesCat. No.: HY-158723CAS No.: 1388156-40-8C17 Dihydro ceramide (d18:0/17:0) is a sphosphingolipid.
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Bucloxic acid
0 ImagesCat. No.: HY-101581CAS No.: 32808-51-8Synonyms: 804CB; Bucloxonic acid; EsfarBucloxic acid is an anti-inflammatory pyrrazole derivative. Bucloxic acid can be used for study of chronic glomerular nephropathies.
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Bencianol
0 ImagesCat. No.: HY-101573CAS No.: 85443-48-7Synonyms: ZY15051Bencianol is a the semisynthetic flavinoid, with anti-spasmogenic activities.
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PCA50941
0 ImagesCat. No.: HY-U00034CAS No.: 136941-85-0PCA50941 is a 1,4-dihydropyridine derivative, used for treatment for cardiovascular disease.
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1-(3-Fluorophenyl)propan-2-one
0 ImagesCat. No.: HY-W611212CAS No.: 1737-19-51-(3-Fluorophenyl)propan-2-one is a precursor in the synthesis of amphetamines.
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α-D-Glucosamine 1-phosphate
0 Imagesα-D-Glucosamine 1-phosphate is a glycosyl donor analog of Glc-1-P. α-D-Glucosamine 1-phosphate acts as a glycosyl donor to produce α(1→4)-linked glucosamine chains in the enzyme-catalyzed polymerization reaction mediated by thermostable α-glucan phosphorylase. α-D-Glucosamine 1-phosphate serves as a glycosyl donor analog to generate a pentasaccharide with a glucosamine residue at the non-reducing end in the maltotetraose glucosamination reaction catalyzed by potato α-glucan phosphorylase. α-D-Glucosamine 1-phosphate is used for the synthesis of amphiphilic block polysaccharides with pH-responsive assembly/disassembly properties.
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1-(2-Trifluoromethylphenyl)piperazine hydrochloride
0 ImagesCat. No.: HY-W714845CAS No.: 40160-26-71-(2-Trifluoromethylphenyl)piperazine hydrochloride is a piperazine.
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Kuwanon S
0 ImagesCat. No.: HY-N16130CAS No.: 100187-67-5Kuwanon S is a flavonoid compound that can be isolated from the root bark of Morus alba L. Kuwanon S is commonly used in organic synthesis and biochemistry experiments.
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Glycol salicylate (Standard)
0 ImagesGlycol salicylate (Standard) is the analytical standard of Glycol salicylate. This product is intended for research and analytical applications. Glycol salicylate is a derivative of salicylic acid and can be used to improve the aesthetic appearance of the skin.
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D-Cysteic acid
0 ImagesCat. No.: HY-W736050CAS No.: 35554-98-4D-Cysteic acid is a competitive inhibitor of the aspartate:alanine antiporter (AspT) from Tetragenococcus halophilus. For L-aspartate self-exchange, D-Cysteic acid has a Ki of 0.14 mM and an IC50 of 0.19 mM; for L-alanine self-exchange, it has a Ki of 5.0 mM and an IC50 of 9.0 mM. D-Cysteic acid occupies a distinct substrate-binding site within the substrate transport pathway of AspT, preventing the binding of natural substrates to the transporter. D-Cysteic acid can be used in studies related to substrate recognition and transport mechanisms of transporters.
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WAY-322454
0 ImagesWAY-322454 is an active molecule.
