2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3823):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N17089
    Nardochalaristolone B
    Nardochalaristolone B is a natural sesquiterpene.
    Nardochalaristolone B
  • HY-N16953
    Lansiumarin A
    Lansiumarin A is a natural coumarin.
    Lansiumarin A
  • HY-N13064
    2,2′,4,4′-Tetrahydroxychalcone
    2,2′,4,4′-Tetrahydroxychalcone (Compound 18) is a selective and potent BACE1 inhibitor with an IC50 of 0.62 μM. 2,2′,4,4′-Tetrahydroxychalcone is a derivative of Isoliquiritigenin (HY-N0102) found in Glycyrrhiza uralensis. 2,2′,4,4′-Tetrahydroxychalcone can block the β-cutting step of amyloid precursor protein (APP), thereby reducing the production of β-amyloid (Aβ) peptide. 2,2′,4,4′-Tetrahydroxychalcone can be used for research of Alzheimer’s disease.
    2,2′,4,4′-Tetrahydroxychalcone
  • HY-N17001
    Tabernaecorymbosine A
    Tabernaecorymbosine A is a natural alkaloid.
    Tabernaecorymbosine A
  • HY-N16792
    Sanggenol F
    Sanggenol F is a natural phenolic compound.
    Sanggenol F
  • HY-115963
    Anticancer agent 38
    Anticancer agent 38 (compound 19), a sulfonylurea derivative, is a potent anticancer agent. Anticancer agent 38 inhibits A431 cell growth with an IC50 of 5.2 µg/mL.
    Anticancer agent 38
  • HY-146025
    Antitumor agent-F10
    Antitumor agent-F10 (Compound F10) is a camptothecin derivative. Antitumor agent-F10 is an orally–bioavailable and potent antitumor agent. Antitumor agent-F10 displays lower acute toxicity than SN-38 does and the solubility of F10 reached 9.86 μg/mL.
    Antitumor agent-F10
  • HY-N7317
    Albatrelin G
    Albatrelin G is a natural phenolic compound.
    Albatrelin G
  • HY-N17619
    Sanggenofuran A
    Sanggenofuran A is a natural product that can be found in mulberry.
    Sanggenofuran A
  • HY-116079
    Diplopterol
    Diplopterol is a hopane compound that can be purified from Rhodopseudomonas palustris TIE-1. Diplopterol acts as a sterol substitute.
    Diplopterol
  • HY-P11461
    Biotin-CRF, human, rat
    Biotin-CRF, human, rat is a biotin-conjugated CRF (human, rat). CRF (human, rat) is a corticotropin-releasing hormone, paraventricular hypothalamic nucleus marker.
    Biotin-CRF, human, rat
  • HY-N16778
    8-Oxoisocorypalmine
    8-Oxoisocorypalmine is a natural alkaloid.
    8-Oxoisocorypalmine
  • HY-N16948A
    (R)-1,5-Epoxy-3-hydroxy-1-(3,4-dihydroxy-5-methoxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)heptane
    (R)-1,5-Epoxy-3-hydroxy-1-(3,4-dihydroxy-5-methoxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)heptane is a natural phenolic compound.
    (R)-1,5-Epoxy-3-hydroxy-1-(3,4-dihydroxy-5-methoxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)heptane
  • HY-P10063
    Cionin
    Cionin is a disulfotyrosyl hybrid of cholecystokinin and gastrin.
    Cionin
  • HY-111221
    PD 113271
    PD 113271 is an active compound.
    PD 113271
  • HY-N9889
    2''-O-E-p-Coumaroylafzelin
    2''-O-E-p-Coumaroylafzelin is a natural flavonoid.
    2''-O-E-p-Coumaroylafzelin
  • HY-N16815
    Embigenin
    Embigenin is a natural flavonoid.
    Embigenin
  • HY-149076
    hGAPDH-IN-1
    hGAPDH-IN-1, a 3-bromo-4,5-dihydroisoxazole derivative, is a specific and potent hGAPDH covalent inhibitor. hGAPDH-IN-1 reduces cancer cell growth in different pancreatic cancer cell lines.
    hGAPDH-IN-1
  • HY-17672
    Jasplakinolide probe-1
    Jasplakinolide probe-1 (Compound 12), a Jasplakinolide (HY-P0027) derivative, is a Jasplakinolide probe. Jasplakinolide probe-1 shows anti-proliferative activity and can inhibit the dynamics of actin, cause the collapse of cell lamellipodia, interfering with the dynamic balance of actin. Jasplakinolide probe-1 can be used for imaging of actin structure in cells conjugated with a fluorescent dye .
    Jasplakinolide probe-1
  • HY-151570
    Anticancer agent 87
    Anticancer agent 87 is a spirooxindole-furan derivative with anticancer activity. Anticancer agent 87 can be used for the research of breast adenocarcinoma and human liver cancer.
    Anticancer agent 87