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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-DY1078
    Acridine Orange 10-Nonyl Bromide (solution)
    Acridine Orange 10-Nonyl Bromide (solution) is a fluorescent probe for cardiolipin (λex: 489 nm, λem: 525 nm).
    Solvent and concentration: DMSO: 10 mM
    Acridine Orange 10-Nonyl Bromide (solution)
  • HY-D1500
    Fluorescent NIR 885
    Fluorescent NIR 885 is a cyanine near-infrared-absorbing dye. Fluorescent NIR 885 can be used as a photoprotective agent (extracted from patent WO2014006589 compound 1-35).
    Fluorescent NIR 885
  • HY-D1928
    ATTO 425 amine
    ATTO 425 Amine is an amine derivative of ATTO 425, the maximum excitation emission wavelength: 439/489 nm.
    ATTO 425 amine
  • HY-148689E
    Cy3 labled SPC4061 sodium
    Cy3 labled SPC4061 sodium is a Cy3 labled SPC4061 sodium.
    Cy3 labled SPC4061 sodium
  • HY-D2938
    BG-PEG11-Cya-NR
    BG-PEG11-Cya-NR is a high-performance, non washable, fluorescent opening probe. BG-PEG11-Cya-NR has very weak fluorescence in polar environments (such as aqueous solutions), while its fluorescence is significantly enhanced in non-polar environments (such as the lipid bilayer of cell membranes).
    BG-PEG11-Cya-NR
  • HY-D3244
    RDDB
    RDDB is a rhodamine-based turn-on fluorescent and colorimetric chemosensor selective for Mn2+, with a limit of detection of 5×10-8 M (excitation wavelength: 480-550 nm; fluorescence signal collection range: >590 nm). In the presence of Mn2+, RDDB undergoes a spirolactam ring-opening reaction of its rhodamine hydrazide moiety, resulting in turn-on fluorescence and a color change. RDDB can be used for intracellular Mn2+ imaging.
    RDDB
  • HY-D3242
    FD-1080 Maleimide
    FD-1080 Maleimide (FD-1080-MAL) is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 can be used for in vivo imaging.
    FD-1080 Maleimide
  • HY-D1904
    D-Luciferin 6'-methyl ether
    D-Luciferin 6'-methyl ether sodium salt is a firefly luciferase inhibitor. D-Luciferin 6'-methyl ether sodium salt is a cofactor in Luc-catalyzed synthesis of dinucleoside polyphosphates.
    D-Luciferin 6'-methyl ether
  • HY-175131
    Prostaglandin D2-biotin
    Prostaglandin D2-biotin is a fluorescent probe that can be used for detecting PGD2.
    Prostaglandin D2-biotin
  • HY-D3140
    MB-m-borate
    MB-m-borate is a double-locked near-infrared fluorescence-activated probe (Ex/Em ≈ 647 nm/684 nm). MB-m-borate undergoes cascade activation by hydrogen peroxide and tyrosinase to release the fluorophore methylene blue, thereby generating a fluorescence activation response. MB-m-borate enables precise detection of melanoma in melanoma cells and mouse models. MB-m-borate can be used for melanoma research.
    MB-m-borate
  • HY-D2888H
    RB-PEG10000-FA
    RB-PEG10000-FA (Rhodamine B-PEG10000-FA) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG10000-FA can be used for cell imaging, folate receptor targeting and detection (Ex/Em=546/610 nm).
    RB-PEG10000-FA
  • HY-D2883D
    RB-PEG3400-SH
    RB-PEG3400-SH (Rhodamine B-PEG3400-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm).
    RB-PEG3400-SH
  • HY-120659
    Gly-Gly-AMC
    Gly-Gly-AMC is a fluorogenic peptide substrate. Gly-Gly-AMC can be used to assess bacterial protease activity of P. aeruginosa and S. aureus.
    Gly-Gly-AMC
  • HY-D3376
    6-Carboxy-H2DCFDA
    6-Carboxy-H2DCFDA (6-Carboxy-2',7'-dichlorodihydrofluorescein) is a non-fluorescent, cell-permeable intracellular ROS indicator. 6-Carboxy-H2DCFDA undergoes oxidation to highly fluorescent carboxy-dichlorofluorescein (Ex/Em = 488/520 nm).
    6-Carboxy-H2DCFDA
  • HY-D3310
    Fluorescein-12-dGTP
    Fluorescein-12-dGTP is a fluorescein-labeled deoxyguanosine triphosphate. Fluorescein-12-dGTP incorporates into complementary allele-specific primers at SNP sites, enabling FRET with cationic conjugated polymer PFP via DNA-PFP electrostatic interactions. Fluorescein-12-dGTP incorporates into G-allele-specific primers for homozygous G/G SNP genotypes to enable genotype discrimination. Fluorescein-12-dGTP serves as a fluorescently labeled nucleotide for homogeneous solution-based SNP and FRET genotyping assays (Ex/Em = 498/517 nm).
    Fluorescein-12-dGTP
  • HY-D3258
    AF660 NHS Ester
    AF 660 NHS ester is a fluorescent dye AF 660 derivative exhibits high fluorescence quantum yield and high photostability. AF 660 NHS ester can form an ester bond with ammonia via the NHS group, and can be used to label proteins, amine-modified oligonucleotides, and other primary amines (R-NH2) containing amine molecules (Ex/Em = 668/698 nm).
    AF660 NHS Ester
  • HY-D1869
    800CW maleimide
    800CW maleimide is an infrared dye that can be used for labeling molecules that contain free sulfhydryl (–SH) groups (Ex: 778 nm; Em: 796 nm). 800CW maleimide binds to plasma proteins.
    800CW maleimide
  • HY-D3182
    AldRed 588-A
    AldeRed 588-A is a fluorescent labeling reagent and a substrate for aldehyde dehydrogenase (ALDH). AldeRed 588-A is metabolized by functionally active ALDH enzymes, thereby specifically labeling viable ALDHbright cell populations with red-shifted fluorescence. AldeRed 588-A supports one-step isolation and sorting of ALDH-expressing cells (including normal stem cells and cancer stem cells), and can be used in combination with green fluorophores for multicolor experimental applications. AldeRed 588-A is widely applicable to research related to various cancers such as bladder cancer, breast cancer, and head and neck cancer.
    AldRed 588-A
  • HY-D0104
    Fluorescein-O-acetate
    Fluorescein-O-acetate is a fluorescent reagent.
    Fluorescein-O-acetate
  • HY-D2797
    Chitosan-Cy7 (MW 2000)
    Chitosan-Cy7 (MW 2000) is a Chitosan labeled with Cy7 (HY-D0825). Chitosan-Cy7 (MW 2000) can be used for fluorescent labeling and imaging.
    Chitosan-Cy7 (MW 2000)
Cat. No. Product Name / Synonyms Application Reactivity