2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10876):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-13502AS
    Mitoxantrone-d8 dihydrochloride
    Mitoxantrone-d8 dihydrochloride is deuterated labeled Mitoxantrone dihydrochloride (HY-13502A). Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor. Mitoxantrone dihydrochloride also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM. Mitoxantrone dihydrochloride induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone dihydrochloride shows antitumor activity. Mitoxantrone dihydrochloride also has anti-orthopoxvirus activity with EC50s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively.
    Mitoxantrone-d<sub>8</sub> dihydrochloride
  • HY-90009AS1
    Tadalafil-13C2,d3-1
    Tadalafil-13C2,d3-1 (IC-351-13C2,d3-1) is the deuterium and 13C-labeled Tadalafil (HY-90009A). Tadalafil (IC-351) is a PDE5 inhibitor with an IC50 value of 1.8 nM.
    Tadalafil-13</sup>C<sub>2</sub>,d<sub>3</sub>-1
  • HY-142140S
    3-epi-25-Hydroxy Vitamin D3-d6
    3-epi-25-Hydroxy Vitamin D3-d6 is the deuterium labeled 3-epi-25-Hydroxy Vitamin D3 (HY-142140). 3-epi-25-Hydroxy Vitamin D3 is the vitamin D metabolite, while vitamin D metabolism highly dependent on macrophage polarization. The C3-epimerase pathway for vitamin D is active in macrophages.
    3-epi-25-Hydroxy Vitamin D3-d<sub>6</sub>
  • HY-W007690S
    Pyridin-4-ol-d5
    Pyridin-4-ol-d5 is the deuterium labeled Pyridin-4-ol (HY-W007690). Pyridin-4-ol is a pyridinol and can be used as synthetic intermediate.
    Pyridin-4-ol-d<sub>5</sub>
  • HY-W700581
    1-(Methyl-d3)-4-nitrosopiperazine
    1-(Methyl-d3)-4-nitrosopiperazine is the deuterium labeled 1-Methyl-4-nitrosopiperazine (HY-W663740). 1-Methyl-4-nitrosopiperazine (MNP; MeNP;N-Methyl-N'-nitrosopiperazine) is a potential impurity in sartans, non-steroidal anti-inflammatory drugs (NSAIDs), and thiazide diuretics.
    1-(Methyl-d<sub>3</sub>)-4-nitrosopiperazine
  • HY-151869S
    Benzenemethanamine,N-(methyl-d3)-,hydrochloride
    		99%
    Benzenemethanamine,N-(methyl-d3)-,hydrochloride is the deuterium labeled Benzenemethanamine,N-(methyl)-,hydrochloride.
    Benzenemethanamine,N-(methyl-d<sub>3</sub>)-,hydrochloride
  • HY-W011683S6
    2'-Deoxyadenosine monohydrate-13C10,15N5 hydrate
    		99.7%
    2'-Deoxyadenosine monohydrate-13C10,15N5 is the 13C and 15N labeled 2'-Deoxyadenosine monohydrate (HY-W011683). 2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine monohydrate inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine monohydrate activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer.
    2'-Deoxyadenosine monohydrate-<sup>13</sup>C<sub>10</sub>,<sup>15</sup>N<sub>5</sub> hydrate
  • HY-W007374S
    2-Bromo-1,3-difluorobenzene-d3
    2-Bromo-1,3-difluorobenzene-d3 is the deuterium labeled 2-Bromo-1,3-difluorobenzene.
    2-Bromo-1,3-difluorobenzene-d<sub>3</sub>
  • HY-W012709S
    DL-2-Aminohexanoic acid-d9
    DL-2-Aminohexanoic acid-d9 is the deuterium labeled DL-2-Aminohexanoic acid.
    DL-2-Aminohexanoic acid-d<sub>9</sub>
  • HY-176359S
    KRAS 2B G12D mutant, Arg-13C6,15N4, Lys-13C6,15N2
    KRAS 2B G12D mutant, Arg-13C36, 15N4, Lys-13C6, 15N2 is the 13C- and 15N-labeled KRAS 2B G12D mutant.
    KRAS 2B G12D mutant, Arg-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N<sub>4</sub>, Lys-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N<sub>2</sub>
  • HY-16271S
    Kevetrin-13C2,15N3 hydrochloride
    Kevetrin (hydrochloride)-13C2,15N3 is the 13C-labeled and 15N-labeled Kevetrin (hydrochloride). Kevetrin hydrochloride is a small molecule and activator of the tumor suppressor protein p53, with potential antineoplastic activity.
    Kevetrin-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N<sub>3</sub> hydrochloride
  • HY-21268S
    Methyl linolenate-13C18
    Methyl linolenate-13C18 is the 13C labeled Methyl linolenate. Methyl linolenate is a polyunsaturated fattly acid (PUFA). It is used in studies on the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids. The IC50 is 60 uM.
    Methyl linolenate-<sup>13</sup>C<sub>18</sub>
  • HY-W004059S1
    Diphenylmethanol-d10
    Diphenylmethanol-d10 (Benzhydrol-d10) is the deuterium labeled Benzhydrol (HY-W004059). Diphenylmethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Diphenylmethanol-d<sub>10</sub>
  • HY-144157S
    N-Acetyl Retigabine-d3 dihydrochloride
    N-Acetyl Retigabine-d3 (dihydrochloride) is the deuterium labeled N-Acetyl Retigabine dihydrochloride.
    N-Acetyl Retigabine-d<sub>3</sub> dihydrochloride
  • HY-143808S
    (S)-Stiripentol-d9
    (S)-Stiripentol-d9 is the deuterium labeled (S)-Stiripentol.
    (S)-Stiripentol-d<sub>9</sub>
  • HY-B2236S3
    DL-Lysine-15N2 hydrochloride
    DL-Lysine-15N2 hydrochloride ((±)-2,6-Diaminocaproic acid-15N2 hydrochloride) is 15N labeled DL-Lysine (HY-B2236). DL-Lysine is a racemic mixture of the D-Lysine and L-Lysine. Lysine is an α-amino acid that is used in the biosynthesis of proteins.
    DL-Lysine-<sup>15</sup>N<sub>2</sub> hydrochloride
  • HY-W700253
    tert-Butyl 4-methylpiperazine-1-carboxylate-d8
    tert-Butyl 4-methylpiperazine-1-carboxylate-d8 is the deuterium labeled tert-Butyl 4-methylpiperazine-1-carboxylate (HY-W050208).
    tert-Butyl 4-methylpiperazine-1-carboxylate-d<sub>8</sub>
  • HY-W754725
    N-Nitrosoephedrine-d3
    N-Nitrosoephedrine-d3 is the deuterium labeled N-Nitrosoephedrine.
    N-Nitrosoephedrine-d<sub>3</sub>
  • HY-110034S
    Didesmethylsibutramine-d7 hydrochloride
    Didesmethylsibutramine-d7 (BTS 54-505-d7) hydrochloride is deuterium labeled Didesmethylsibutramine hydrochloride.
    Didesmethylsibutramine-d<sub>7</sub> hydrochloride
  • HY-100657S
    Meta-Fexofenadine-d6
    Meta-Fexofenadine-d6 is the deuterium labeled meta-Fexofenadine. meta-Fexofenadine (meta-MDL-16455) is an impurity of Fexofenadine. Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial.
    Meta-Fexofenadine-d<sub>6</sub>