2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.

Liposome Related Products (1007):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W587499
    2-Arachidonoyl-sn-glycero-3-phosphocholine
    2-Arachidonoyl-sn-glycero-3-phosphocholine is a phospholipid molecule that is a major component of the plasma membrane. It is a phospholipid molecule that is involved in the regulation of membrane fluidity, signal transduction, cell-cell communication, and mediator of inflammation.
    2-Arachidonoyl-sn-glycero-3-phosphocholine
  • HY-W142596
    1,2-DImyristoyl-rac-glycero-3-phosphocholine
    		99.79%
    1,2-DImyristoyl-rac-glycero-3-phosphocholine (DMPC), a zwitterionic phospholipid, is chosen as a simple eukaryotic cell membrane, mimicking the neutral charge of the surface membrane of eukaryotic plasma membranes.
    1,2-DImyristoyl-rac-glycero-3-phosphocholine
  • HY-172476
    DSPE-PEG2000-YIGSR
    DSPE-PEG2000-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG2000-YIGSR can be used for drug delivery.
    DSPE-PEG2000-YIGSR
  • HY-W440954
    Stearic acid-PEG2000-CH2CO2H
    Stearic acid-PEG2000-CH2CO2H is a heterobifunctional polyPEG with 18-carbon aliphatic chain and carboxyl. The polymer has stearic acid as the hydrophobic tail and PEG as the hydrophilic chain, therefore it forms micelles in water. Carboxyl can react with amine in the presence of activator, such as HATU/EDC to generate a stable amide bond. Reagent grade, for research use only.
    Stearic acid-PEG2000-CH2CO2H
  • HY-172690
    DSPE-PEG2000-THRPPMWSPVWP
    DSPE-PEG2000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells.
    DSPE-PEG2000-THRPPMWSPVWP
  • HY-147071
    1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine
    1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine (DAPE) is a phospholipid phosphatidylethanolamine. Unlike other phospholipid phosphatidylethanolamines, 1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine has no significant effect on protein phosphatase PP2A activity and does not inhibit insulin-stimulated GLUT4 translocation.
    1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine
  • HY-159714
    Lipid HTO12
    		98.50%
    Lipid HTO12 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid HTO12 is a carrier for both siRNA and mRNA.
    Lipid HTO12
  • HY-P11456A
    Lipopeptide CPK4 TFA
    		98.92%
    Lipopeptide CPK4 TFA is a Cholesterol (HY-N0322)-modified peptide K4 [(KIAALKE)3]. Lipopeptide CPK4 TFA is capable of coiled-coil formation when attached to liposomes. Lipopeptide CPK4 TFA triggers membrane fusion between liposomes and living cells with concomitant efficient cytosolic delivery of a variety of compounds such as fluorescent dyes Propidium Iodide (PI) (HY-D0815) and TO-PRO-3 iodide (HY-117070), and Doxorubicin (DOX) (HY-15142A). Lipopeptide CPK4 TFA can be used for drug delivery research.
    Lipopeptide CPK4 TFA
  • HY-167015
    1O14
    		99.0%
    1O14 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. 1O14 can be used in the preparation of liposomes.
    1O14
  • HY-159854
    C14-O2
    		99.00%
    C14-O2 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads.
    C14-O2
  • HY-N15956
    DMG-PEG(2k)-DBCO
    DMG-PEG(2k)-DBCO is a Clickable PEG lipid containing a DBCO group. DSPE-PEG8-DBCO can be used to prepare lipid nanoparticles for drug delivery.
    DMG-PEG(2k)-DBCO
  • HY-172526
    4A3-SCC-10
    4A3-SCC-10 is a biodegradable ionizable lipid containing disulfide bonds. 4A3-SCC-10 can be used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. 4A3-SCC-10 can be used for broad applications such as gene editing, vaccine, and cancer detection.
    4A3-SCC-10
  • HY-W440690
    Cholesterol-PEG2000-amine
    Cholesterol-PEG2000-amine is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles.
    Cholesterol-PEG2000-amine
  • HY-160580
    G1-OC2-K3-E10
    		98.9%
    G1-OC2-K3-E10 is an ionizable lipid, and can be used for delivery of mRNA in lipid nanoparticles (LNPs).
    G1-OC2-K3-E10
  • HY-165604
    C14-490
    		98%
    C14-490, an ionizable cationic lipid (pKa = 5.94), is used for the synthesis of lipid nanoparticles (LNPs). C14-490 LNPs is used as the basis for subsequent study of in utero gene editing in HSCs. C14-490 LNPs are used to encapsulate SpCas9 mRNA and TTR sgRNA using optimized B5 formulation parameters and surface conjugation to CD45 antibody F(ab’)2 fragments-Systematically optimized Targeted Editing Machinery LNPs (STEM LNPs).
    C14-490
  • HY-142997
    DOSPA
    DOSPA is a cationic lipid. DOSPA can form lipid nanoparticles with DOPE (HY-112005) to serve as a carrier for nucleic acid transfection. DOSPA is applicable in research related to drug delivery.
    DOSPA
  • HY-171728
    Azide-PEG2-amide-C14-COOH
    		98.0%
    Azide-PEG2-amide-C14-COOH (Compound LP-379-p) is a lipid-containing compound. Azide-PEG2-amide-C14-COOH facilitates the delivery of oligonucleotide-based reagents to certain cell types or adipose tissue.
    Azide-PEG2-amide-C14-COOH
  • HY-144000A
    DSPE-PEG2000-PDP
    DSPE-PEG2000-PDP is a phospholipid PEG conjugate that can be used in drug delivery applications.
    DSPE-PEG2000-PDP
  • HY-W440939
    Stearic acid-PEG3400-FITC
    Stearic acid-PEG3400-FITC is a PEG lipid which forms micelles in water and can be used for drug delivery applications. The FITC fluorescent can be easily traced by miscroscopy. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
    Stearic acid-PEG3400-FITC
  • HY-141614
    1,2-Diarachidoyl-sn-glycero-3-phosphocholine
    		98.0%
    1,2-Diarachidoyl-sn-glycero-3-phosphocholine (1,2-DAPC) is a phospholipid containing the saturated long-chain (20:0) arachidic acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
    1,2-Diarachidoyl-sn-glycero-3-phosphocholine