2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.

Liposome Related Products (1007):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-172328A
    (S)-O12-D3-I3
    (S)-O12-D3-I3 is an ionizable cationic lipid (pKa = 6.39). (S)-O12-D3-I3 can be used to prepare lipid nanoparticles (LNPs) for in vitro and in vivo siRNA delivery. (S)-O12-D3-I3 can also be used in research on cancers such as liver cancer and breast cancer.
    (S)-O12-D3-I3
  • HY-172683
    DSPE-PEG1000-GRGDS
    DSPE-PEG1000-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG1000-GRGDS can be used for drug delivery.
    DSPE-PEG1000-GRGDS
  • HY-160577
    DOG-IM4
    DOG-IM4 can be used to synthesize nanoparticles to deliver antigen-encoding nucleic acids. It could be used to try to target autoimmune diseases, rare blood or metabolic diseases, allergies, cancer or infectious diseases.
    DOG-IM4
  • HY-142982
    Palmitoyloleoylphosphatidylglycerol
    Palmitoyloleoylphosphatidylglycerol is an anionic surfactant lipid. Palmitoyloleoylphosphatidylglycerol suppresses Der p 2-stimulated inflammatory responses in lung epithelial cells and macrophages.
    Palmitoyloleoylphosphatidylglycerol
  • HY-172491
    DSPE-PEG2000-ESBP
    DSPE-PEG2000-ESBP is a PEG compound which composed of DSPE and a E-selectin-binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells.
    DSPE-PEG2000-ESBP
  • HY-144013E
    18:0 mPEG3000 PE ammonium
    18:0 mPEG3000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
    18:0 mPEG3000 PE ammonium
  • HY-W440899
    DSPE-PEG1000-SPDP
    DSPE-PEG1000-SPDP is a thiol reactive PEG lipid. The polymer is amphiphilic and spontaneously forms lipid bilayer in water. It can be used to encapsulate nutrients or therapeutics for targeted drug delivery, for example mRNA or DNA vaccine, liposomal doxorubicin for anti tumor.
    DSPE-PEG1000-SPDP
  • HY-172482
    DSPE-PEG2000-TAASGVRSMH
    DSPE-PEG2000-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG2000-TAASGVRSMH can be used for drug delivery.
    DSPE-PEG2000-TAASGVRSMH
  • HY-155930
    18:1 PEG350 PE ammonium
    18:1 PEG350 PE ammonium (DOPE-PEG350 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
    18:1 PEG350 PE ammonium
  • HY-W440727
    Cholesterol-PEG2000-Vinylsulfone
    Cholesterol-PEG2000-Vinylsulfone is a thiol reactive polyPEG via thiol-ene reaction to form a thioether bond. It can self-assemble in water and is used to prepare liposome as drug vehicle for targeted delivery into tissues.
    Cholesterol-PEG2000-Vinylsulfone
  • HY-172275
    DSPE-PEG1000-Cys-SRNLIDC (Disulfide bridge: Cys1-Cys8)
    DSPE-PEG1000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG1000-pPB can be used for drug delivery.
    DSPE-PEG1000-Cys-SRNLIDC (Disulfide bridge: Cys1-Cys8)
  • HY-W440682
    C13-113-tri-tail
    C13-113-tri tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a tertiary amine linker. C13-113-tri tail can be formulated into a lipid nanoparticle (LNP).
    C13-113-tri-tail
  • HY-W800843
    tert-Butyl 3-(7-((undecan-3-yloxy)carbonyl)heptylamino)propylcarbamate
    tert-Butyl 3-(7-((undecan-3-yloxy)carbonyl)heptylamino)propylcarbamate is an aminolipid featuring a Boc-protected primary amine, a propylamine spacer attached to an octanoate chain and a C11 chain.
    tert-Butyl 3-(7-((undecan-3-yloxy)carbonyl)heptylamino)propylcarbamate
  • HY-172271C
    DSPE-PEG3400-Mal-Cys-CGNKRTRGC (Disulfide bridge: Cys2-Cys10)
    DSPE-PEG3400-LyP-1 is a PEG compound which composed of DSPE and a nine residue peptide (LyP-1) (HY-P2526). LyP-1 targets tumor-associated lymphatic vessels and macrophages.
    DSPE-PEG3400-Mal-Cys-CGNKRTRGC (Disulfide bridge: Cys2-Cys10)
  • HY-172694
    DSPE-PEG5000-TH
    DSPE-PEG5000-TH is a PEG compound which composed of DSPE and a pH-responsive cell penetrating peptide (TH). TH is activated in an acidic environment (such as the tumor microenvironment) and can selectively carry small molecules, oligonucleotides, proteins, etc. into tumor cells.
    DSPE-PEG5000-TH
  • HY-143211
    Murapalmitine
    Murapalmitine is the component of liposomes for drug delivery.
    Murapalmitine
  • HY-158709
    Cho-es-Lys
    Cho-es-Lys is a cationic lipid synthesized by coupling natural cholesterol and amino acids, which has high gene transfection efficiency. Cho-es-Lys can be used in drug delivery research.
    Cho-es-Lys
  • HY-172469
    DSPE-PEG1000-GE11
    DSPE-PEG1000-GE11 is a PEG compound which composed of DSPE and an EGFR targeting peptide (GE11). GE11 can be used for EGFR overexpressed cancer cells. DSPE-PEG1000-GE11 can be used for drug delivery.
    DSPE-PEG1000-GE11
  • HY-148830
    Piperazine-bis(ethyl octadeca-9,12-dienoate)
    Piperazine-bis(ethyl octadeca-9,12-dienoate) is a cationic lipid extracted from patent WO2023036148A1, and can be used for the generation of Lipid nanoparticles (LNPs).
    Piperazine-bis(ethyl octadeca-9,12-dienoate)
  • HY-141489
    DSPE-PEG2000-Carboxy NHS sodium
    DSPE-PEG2000-Carboxy NHS sodium is a linker. DSPE-PEG2000-Carboxy NHS sodium enables conjugation of targeting peptides to lipid nanoparticles after their preparation. DSPE-PEG2000-Carboxy NHS sodium is applicable to the research of hereditary retinal degeneration.
    DSPE-PEG2000-Carboxy NHS sodium