2. TGF-beta/Smad
  3. TGF-β Receptor
  4. ALK5-IN-10

ALK5-IN-10 (Compound 5d) is a TGF-β type I receptor kinase ALK5 inhibitor, with IC50s of 0.007 and 1.98 μM for ALK5 and p38α, respectively. ALK5-IN-10 can be used for the research of cancer.

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ALK5-IN-10

ALK5-IN-10 Chemical Structure

CAS No. : 1352608-94-6

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1 mg Obtenir un devis 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
5 mg Obtenir un devis 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
10 mg Obtenir un devis 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
25 mg Obtenir un devis 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
50 mg Obtenir un devis 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
100 mg   Obtenir un devis  
200 mg   Obtenir un devis  
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ALK5-IN-10 Related Antibodies

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ALK1 ALK2 ALK3 ALK4 ALK5 ALK6 ALK7 TGFβR2 ACVR2A ACVR2B BMP

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Description

ALK5-IN-10 (Compound 5d) is a TGF-β type I receptor kinase ALK5 inhibitor, with IC50s of 0.007 and 1.98 μM for ALK5 and p38α, respectively. ALK5-IN-10 can be used for the research of cancer[1].

Cellular Effect
Cell Line Type Value Description References
Sf9 IC50
0.007 μM
Compound: 12d
Inhibition of human recombinant ALK5 expressed in insect Sf9 cells using casein as substrate by radioisotopic assay
Inhibition of human recombinant ALK5 expressed in insect Sf9 cells using casein as substrate by radioisotopic assay
[PMID: 24786585]
Masse moléculaire

460.33

Formule

C22H18BrN7
CAS No.
SMILES

BrC1=CC=CC=C1NCC2=NC(C3=CN4C(C=C3)=NC=N4)=C(C5=NC(C)=CC=C5)N2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
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ALK5-IN-10 Related Classifications

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Keywords:

ALK5-IN-101352608-94-6TGF-β ReceptorTransforming growth factor beta receptorsp38αcancerTGF-βInhibitorinhibitorinhibit

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