Amantadine-d15 hydrochloride
Based on 1 Customer Validation
Amantadine-d15 hydrochloride is deuterated labeled Amantadine. Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research.
For research use only. We do not sell to patients.
- Formula: C10H3D15ClN
- Molecular Weight:202.80
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 665-66-7
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Molecular Weight 202.80
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Formula C10H3D15ClN
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SMILES
NC1(C([2H])([C@@]2(C([2H])([C@]([2H])(C1([2H])[2H])C([2H])([C@]3(C2([2H])[2H])[2H])[2H])[2H])[2H])[2H])C3([2H])[2H].Cl
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Synonyms
1-Adamantanamine hydrochloride-d15
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Amantadine-d15
- 1-Adamantanamine hydrochloride-d15
- Isotope-Labeled Compounds
- M2 proton channel
- antiviral
- Parkinson's disease
- Vero E6 cells
- antiviral drugs
- Covid-19
- SARS-CoV-2
- orthopoxvirus
- memory impairment
- Postoperative cognitive dysfunction
- POCD
- Neuroinflammation
- HCC cells
- HepG2
- SMMC?7721
- hepatitis C virus
- anticancer
- liver cancer
- Inhibitor
- inhibitor
- inhibit