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Cat. No.: HY-156596A

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Aneratrigine hydrochloride

Aneratrigine hydrochloride is a selective Nav1.7 inhibitor with an IC₅₀ of 19 nM. Aneratrigine hydrochloride is applicable for pain-related research.

For research use only. We do not sell to patients.

CAS No.: 2097163-75-0
Formula: C₁₉H₂₁Cl₂F₂N₅O₂S₂
Molecular Weight:524.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Aneratrigine hydrochloride Chemical Structure

CAS No.: 2097163-75-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Aneratrigine hydrochloride is a selective Nav1.7 inhibitor with an IC₅₀ of 19 nM. Aneratrigine hydrochloride is applicable for pain-related research^[1].

IC₅₀ & Target

Na_v1.7

19 nM (IC₅₀)

All Sodium Channel Isoforms :

In Vitro

Aneratrigine hydrochloride potently inhibits Nav1.7 channels with an IC₅₀ of 19 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2097163-75-0
Molecular Weight 524.44
Formula C₁₉H₂₁Cl₂F₂N₅O₂S₂
SMILES

O=S(NC1=CSC=N1)(C2=C(F)C=C(NC3=CC=C(C=C3N(CCNC)C)F)C(Cl)=C2)=O.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Cha KI, et al. Enhancing Chemical Stability and Bioavailability of Aneratrigine Capsules via Dry Granulation: Addressing Stability Challenges in Sodium Bicarbonate-Containing Formulations for Clinical Development. Pharmaceutics. 2025;17(8):1047. Published 2025 Aug 12. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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Aneratrigine hydrochloride

All Sodium Channel Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Aneratrigine hydrochloride Related Classifications

HY-156596A Related Classifications