Anti-Mouse CXCL10 Antibody (1F11)
Based on 1 Customer Validation
Anti-Mouse CXCL10 Antibody (1F11) is a mouse CXCL10 antibody. Anti-Mouse CXCL10 Antibody (1F11) blocks the activity of CXCL10 and inhibits GPCR-dependent interstitial motility of Th1 cells in inflamed dermis. Anti-Mouse CXCL10 Antibody (1F11) can be used for research on inflammation-related diseases. Recommended isotype control: Polyclonal Armenian hamster IgG, Isotype Control (HY-P990305).
For research use only. We do not sell to patients.
- Purity : 97.56%
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Isotype
Armenian Hamster IgG
Recommend Isotype Controls
Species Reactivity
Mouse
IC50 & Target
[1]|
CXCL10 |
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:BALB/c; DO11.10 TCR transgenic (OVA-specific)[1]
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Dosage:500 µg
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Administration:i.v.; single dose
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Result:Significantly reduced the average velocity of Th1 cells in the inflamed dermis.
Left Th2 cell average velocity unaffected.
Significantly reduced Th1 cell motility in co-transfer experiments with Th1 and Th2 cells, with no impact on Th2 cell motility in the same tissue volume.
Gene ID
Accession
P17515
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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Product Image
Application
in vitro neutralization of CXCL10; in vivo neutralization of CXCL10; in vivo inhibition of T cell re
Chemical Information
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Appearance Liquid
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Color Colorless to light yellow
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (259 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)