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KA1 Antibody (YA4305)(PBS only)

(Synonyms: KA1; EAA1; GRIK; GluK4)

KA1 Antibody (YA4305) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to KA1.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2b

  • Application:

    IHC-P, ICC/IF, FC, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • KA1 Antibody (YA4305)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:200-1:1000 1:200-1:1000 1:200-1:400 1:10000

Product Details

Description

KA1 Antibody (YA4305) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to KA1.

  • Host Mouse
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 107 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 107 kDa
Immunogen

Purified recombinant fragment of human GRIK4 (AA: extra 21-166) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG2b

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    KA1 is an Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel. Cannot form functional channels on its own. Shows channel activity only in heteromeric assembly with GRIK1, GRIK2 and GRIK3 subunits[1].

  • Subcellular Localization

    Cell membrane; Multi-pass membrane protein; Postsynaptic cell membrane; Multi-pass membrane protein; Presynaptic cell membrane; Multi-pass membrane protein

  • Subunit

    Homodimer. Can form functional heteromeric receptors with GRIK1, GRIK2 and GRIK3

  • SwissProt ID

    Q16099

  • Gene ID
    2900 [NCBI]
  • Synonyms

    KA1; EAA1; GRIK; GluK4

KA1 Antibody (YA4305)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • KA1 Antibody (YA4305)(PBS only) Product Image