Benralizumab (FUT8-KO)
Based on 1 Customer Validation
Benralizumab (FUT8-KO) (MEDI-563 (FUT8-KO)) is an anti-IL-5Rα monoclonal antibody expressed in cells with the fucosyltransferase 8 gene (FUT8) knocked out. Benralizumab (FUT8-KO) can be used in research on severe eosinophilic asthma.
For research use only. We do not sell to patients.
- CAS No.: 1044511-01-4
- Molecular Weight:146.08 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
IL-5Rα |
Chemical Information
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CAS No. 1044511-01-4
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Molecular Weight 146.08 kDa
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SMILES
[Benralizumab (FUT8-KO)]
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Synonyms
MEDI-563 (FUT8-KO); BIW-8405 (FUT8-KO); KHK4563 (FUT8-KO)
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Menzies-Gow A, et al. Corticosteroid tapering with benralizumab treatment for eosinophilic asthma: PONENTE Trial. ERJ Open Res. 2019;5(3):00009-2019. Published 2019 Sep 25. [Content Brief]
[2]. Kolbeck R, et al. MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function. J Allergy Clin Immunol. 2010;125(6):1344-1353.e2. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Benralizumab (FUT8-KO) Related Classifications
HY-P9923B Related Classifications
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