Activated CDC42 kinase 1

[1]. Noriko Yokoyama, et al. Purification and enzyme activity of ACK1. Methods Enzymol. 2006;406:250-60. [Content Brief]

[2]. Kiran Mahajan, et al. Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation. PLoS One. 2010 Mar 19;5(3):e9646. [Content Brief]

[3]. Katarzyna Modzelewska, et al. Ack1 mediates Cdc42-dependent cell migration and signaling to p130Cas. J Biol Chem. 2006 Dec 8;281(49):37527-35. [Content Brief]

[4]. Lene Melsaether Grøvdal, et al. Dysregulation of Ack1 inhibits down-regulation of the EGF receptor. Exp Cell Res. 2008 Apr 1;314(6):1292-300. [Content Brief]

[5]. Victoria Prieto-Echagüe, et al. Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1. J Biol Chem. 2010 Apr 2;285(14):10605-15. [Content Brief]

[6]. Y Liu, et al. Dasatinib inhibits site-specific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases. Oncogene. 2010 Jun 3;29(22):3208-16. [Content Brief]

[7]. Edward Htun van der Horst, et al. Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1. Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15901-6. [Content Brief]

[8]. J Kato, et al. Activation of the guanine nucleotide exchange factor Dbl following ACK1-dependent tyrosine phosphorylation. Biochem Biophys Res Commun. 2000 Feb 5;268(1):141-7. [Content Brief]

[9]. M Teo, et al. The tyrosine kinase ACK1 associates with clathrin-coated vesicles through a binding motif shared by arrestin and other adaptors. J Biol Chem. 2001 May 25;276(21):18392-8. [Content Brief]

[10]. Noriko Yokoyama, et al. Phosphorylation of WASP by the Cdc42-associated kinase ACK1: dual hydroxyamino acid specificity in a tyrosine kinase. J Biol Chem. 2005 Dec 23;280(51):42219-26. [Content Brief]

[11]. Lin Pao-Chun, et al. Cytoplasmic ACK1 interaction with multiple receptor tyrosine kinases is mediated by Grb2: an analysis of ACK1 effects on Axl signaling. J Biol Chem. 2009 Dec 11;284(50):34954-63. [Content Brief]

[12]. Jillian Howlin, et al. TNK2 preserves epidermal growth factor receptor expression on the cell surface and enhances migration and invasion of human breast cancer cells. Breast Cancer Res. 2008;10(2):R36. [Content Brief]