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AG1523

Definition:

AG1523 is a human Fibroblast of foreskin finite cell line derived from Foreskin, skin. AG1523 has a finite proliferative lifespan and retains primary-cell-like characteristics. AG1523 is used to investigate cellular phenotype, signal transduction, and pharmacological response in a controlled cellular system.

References:

[1]. Westermark B, et al. Human melanoma cell lines of primary and metastatic origin express the genes encoding the chains of platelet-derived growth factor (PDGF) and produce a PDGF-like growth factor. Proceedings of the National Academy of Sciences of the United States of America. 1986;83(19):7197-200.

[2]. Heldin NE, et al. Aberrant expression of receptors for platelet-derived growth factor in an anaplastic thyroid carcinoma cell line. Proceedings of the National Academy of Sciences of the United States of America. 1988;85(23):9302-6.

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