C3H/3T3
Definition:
C3H/3T3 denotes a mouse embryonic fibroblast culture system derived from the C3H strain and maintained using a 3T3 transfer schedule[1][2]; Published work distinguishes parental C3H/3T3-type cells from spontaneous, chemical, and viral transformants, showing that transformation history materially changes phenotype and tumorigenic behavior[2]. C3H/3T3 cultures have also been used for mouse adenovirus propagation and infection studies[3]. Because the input lacks a repository accession, substrain, and clone or transformation suffix, it supports only a partial identity; database records should preserve those qualifiers before assigning specific morphology, molecular features, transformation status, or application data to the material.
References:
Biomedical Dictionary
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