Condensin-2 complex subunit G2

Definition:

Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.

References:

[1]. Takao Ono, et al. Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells. Cell. 2003 Oct 3;115(1):109-21. [Content Brief]

[2]. Tahir N Khan, et al. Mutations in NCAPG2 Cause a Severe Neurodevelopmental Syndrome that Expands the Phenotypic Spectrum of Condensinopathies. Am J Hum Genet. 2019 Jan 3;104(1):94-111. [Content Brief]

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