Cyclin-dependent kinase 15

Definition:

Serine/threonine-protein kinase that acts like an antiapoptotic protein that counters TRAIL/TNFSF10-induced apoptosis by inducing phosphorylation of BIRC5 at 'Thr-34'.

References:

[1]. Mi Hee Park, et al. ALS2CR7 (CDK15) attenuates TRAIL induced apoptosis by inducing phosphorylation of survivin Thr34. Biochem Biophys Res Commun. 2014 Jul 18;450(1):129-34. [Content Brief]

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