Cyclin-T1
Definition:
References:
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[1]. Y T Kwak, et al. Role of the human and murine cyclin T proteins in regulating HIV-1 tat-activation. J Mol Biol. 1999 Apr 23;288(1):57-69. [Content Brief]
[2]. Huasong Lu, et al. Phase-separation mechanism for C-terminal hyperphosphorylation of RNA polymerase II. Nature. 2018 Jun;558(7709):318-323. [Content Brief]
[3]. D Ivanov, et al. Cyclin T1 domains involved in complex formation with Tat and TAR RNA are critical for tat-activation. J Mol Biol. 1999 Apr 23;288(1):41-56. [Content Brief]
[4]. Zhiyuan Yang, et al. Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4. Mol Cell. 2005 Aug 19;19(4):535-45. [Content Brief]
[5]. Huanyi Fu, et al. Poly(ADP-ribosylation) of P-TEFb by PARP1 disrupts phase separation to inhibit global transcription after DNA damage. Nat Cell Biol. 2022 Apr;24(4):513-525. [Content Brief]
[6]. Moon Kyoo Jang, et al. The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription. Mol Cell. 2005 Aug 19;19(4):523-34. [Content Brief]
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