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IST-MES1

Definition:

IST-MES1 is a human cancer cell line derived from Pleural effusion and associated with Pleural epithelioid mesothelioma and Pleural mesothelioma. IST-MES1 is immortalized or transformed by Asbestos. IST-MES1 is used as an in vitro model of Pleural epithelioid mesothelioma and Pleural mesothelioma to investigate tumor-cell growth, cell survival, and pharmacological response.

References:

[1]. Orengo AM, et al. Establishment of four new mesothelioma cell lines: characterization by ultrastructural and immunophenotypic analysis. The European respiratory journal. 1999;13(3):527-34.

[2]. Bignell GR, et al. Signatures of mutation and selection in the cancer genome. Nature. 2010;463(7283):893-8.

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