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IST-SL1

Definition:

IST-SL1 is a human cancer cell line derived from Supraclavicular lymph node and associated with Lung small cell carcinoma and Small cell lung cancer. Its continuous tumor-cell growth supports reproducible mechanistic and pharmacological experiments. IST-SL1 is used as an in vitro model of Lung small cell carcinoma and Small cell lung cancer to investigate tumor-cell growth, cell survival, and pharmacological response.

References:

[1]. Bignell GR, et al. Signatures of mutation and selection in the cancer genome. Nature. 2010;463(7283):893-8.

[2]. Dutil J, et al. An Interactive Resource to Probe Genetic Diversity and Estimated Ancestry in Cancer Cell Lines. Cancer research. 2019;79(7):1263-1273.

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