Oxoeicosanoid receptor 1
Definition:
Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins.
References:
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[1]. Takeshi Hosoi, et al. Identification of a novel human eicosanoid receptor coupled to G(i/o). J Biol Chem. 2002 Aug 30;277(35):31459-65. [Content Brief]
[2]. Carol E Jones, et al. Expression and characterization of a 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid receptor highly expressed on human eosinophils and neutrophils. Mol Pharmacol. 2003 Mar;63(3):471-7. [Content Brief]
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