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TERT-RPE1

Definition:

TERT-RPE1 is a human Retinal pigment epithelial cell telomerase immortalized cell line derived from Eye, retina, retinal pigment epithelium. Its stable in vitro growth supports reproducible mechanistic and pharmacological experiments. TERT-RPE1 is used to investigate cellular phenotype, signal transduction, and pharmacological response in a controlled cellular system.

References:

[1]. Bodnar AG, et al. Extension of life-span by introduction of telomerase into normal human cells. Science (New York, N.Y.). 1998;279(5349):349-52.

[2]. Rambhatla L, et al. In vitro differentiation capacity of telomerase immortalized human RPE cells. Investigative ophthalmology & visual science. 2002;43(5):1622-30.

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