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UACC-903

Definition:

UACC-903 is a human cancer cell line derived from Back and associated with Cutaneous melanoma. Its continuous tumor-cell growth supports reproducible mechanistic and pharmacological experiments. UACC-903 is used as an in vitro model of Cutaneous melanoma to investigate tumor-cell growth, cell survival, and pharmacological response.

References:

[1]. Cornil I, et al. Fibroblast cell interactions with human melanoma cells affect tumor cell growth as a function of tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 1991;88(14):6028-32.

[2]. Goodall ML, et al. Development of potent autophagy inhibitors that sensitize oncogenic BRAF V600E mutant melanoma tumor cells to vemurafenib. Autophagy. 2014;10(6):1120-36.

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