CA IX/VEGFR-2-IN-3
CA IX/VEGFR-2-IN-3 (Compound 6i) is an inhibitor of Carbonic Anhydrase IX and VEGFR-2, with IC50 values of 41 and 48 nM, respectively. CA IX/VEGFR-2-IN-3 exhibits anticancer activity, inhibiting the growth of MCF-7 breast cancer cells (with an IC50 of 22.33 μM) and mouse fibroblast cell line 3T3 (where cell viability is less than 40% at a concentration of 100 μM). CA IX/VEGFR-2-IN-3 can be used for research in the field of cancer treatment.
For research use only. We do not sell to patients.
- Formula: C19H16ClN3O5S2
- Molecular Weight:465.93
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All VEGFR Isoforms
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Biological Activity
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VEGFR2 48 nM (IC50) |
CA Ⅱ 41 nM (IC50) |
Chemical Information
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Molecular Weight 465.93
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Formula C19H16ClN3O5S2
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SMILES
O=C(NC1=CC=C(C)C(S(=O)(N)=O)=C1)CN(C/2=O)C(SC2=C/C3=CC=C(Cl)C=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)