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Cat. No.: HY-N16677

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Abiesadine I

Abiesadine I is a diterpenoid inhibitor targeting LPS-induced NO production (IC₅₀>100 μg/mL) that can be isolated from Abies georgei. Abiesadine I inhibits LPS-induced nitric oxide (NO) production in RAW264.7 macrophages, exhibiting anti-inflammatory activity.

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CAS No.: 1210347-50-4
Formule: C₂₄H₃₄O₅
Masse moléculaire:402.52

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Abiesadine I Chemical Structure

CAS No.: 1210347-50-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Voir tous les produits spécifiques à Isoform NO Synthase :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	IC₅₀	100 μg/mL Compound: 9, Abiesadine I	Inhibition of TNF-alpha-induced NF-kappaB activity in human pNF-kappaB-luc-293 cells Inhibition of TNF-alpha-induced NF-kappaB activity in human pNF-kappaB-luc-293 cells	[PMID: 20022253]

Chemical Information

CAS No. 1210347-50-4
Masse moléculaire 402.52
Formule C₂₄H₃₄O₅
SMILES

C[C@@]12[C@](CCC3=CC(C(C)(O)C)=CC=C32)([H])[C@@](C)(CCC1)COC(CCC(O)=O)=O
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Plants
- Pinaceae
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Yang XW, et al. Isolation, structure, and bioactivities of abiesadines A-Y, 25 new diterpenes from Abies georgei Orr. Bioorg Med Chem. 2010 Jan 15;18(2):744-54. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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