Acrofolione A
Acrofolione A is an acetophenone dimer isolated from Acronychia pendunculata with anticancer effects. Acrofolione A induces G0/G1 phase cell cycle arrest and apoptosis in human NALM-6 pre-B cell leukaemia cells. Acrofolione A can be used for leukaemia research.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 820975-61-9
- Formule: C32H42O9
- Masse moléculaire:570.67
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Voir tous les produits spécifiques à Isoform Caspase
More
Activité biologique
Acrofolione A (48 h) suppresses the growth of NALM-6, K562 and HPB-ALL cells with IC50 values of 16.7, 17.9, and 10.1 μM, respectively[1].
Acrofolione A (10-20 μM, 6-48 h) induces G0/G1-phase cell cycle arrest and promotes apoptosis in NALM-6 cells, as demonstrated by decreased mitochondrial membrane potential, elevated caspase 3/7 activity, increased levels of cleaved PARP and cleaved caspase-3/7, and reduced expression of survivin protein[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 820975-61-9
-
Masse moléculaire 570.67
-
Formule C32H42O9
-
SMILES
CC(C)CC(C1=C(C(C/C=C(C)\C)=C(C(C(C)=O)=C1O)OC)O)C2=C3C(CC(O3)C(C)(O)C)=C(C(C(C)=O)=C2O)O
-
Structure Classification
-
Initial Source
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Acrofolione A Related Classifications
HY-N16567 Related Classifications
Powered by Bioz