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Cat. No.: HY-107322AS1

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Barnidipine-d₅

(Synonyms: Mepirodipine-d5; YM-09730-5-d5 Free base)

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Barnidipine-d₅ is the deuterium-labeled Barnidipine (HY-107322A). Barnidipine-d₅ (Mepirodipine) is an L-type calcium antagonist (CaA) with high affinity for [³H] initrendipine binding sites (K_i=0.21 nmol/l), has selective action against CaA receptors. Barnidipine-d₅ (Mepirodipine) is an antihypertensive agent and acts by the reduction of peripheral vascular resistance secondary to its vasodilatory action.

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Pureté: 98.97%
CAS No.: 2771469-19-1
Formule: C₂₇H₂₄D₅N₃O₆
Masse moléculaire:496.57

Stockage:

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Barnidipine-d₅ Chemical Structure

CAS No.: 2771469-19-1

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Activité biologique
- Description
- In Vitro
- Application
Chemical Information
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Activité biologique

Description

Barnidipine-d₅ is the deuterium-labeled Barnidipine (HY-107322A). Barnidipine-d₅ (Mepirodipine) is an L-type calcium antagonist (CaA) with high affinity for [³H] initrendipine binding sites (K_i=0.21 nmol/l), has selective action against CaA receptors^[1]. Barnidipine-d₅ (Mepirodipine) is an antihypertensive agent and acts by the reduction of peripheral vascular resistance secondary to its vasodilatory action^[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 2771469-19-1
Unlabeled Cas 104713-75-9
Appearance Solid
Masse moléculaire 496.57
Formule C₂₇H₂₄D₅N₃O₆
Color Off-white to light yellow
SMILES

CC1=C([C@@H](C2=CC([N+]([O-])=O)=CC=C2)C(C(OC)=O)=C(N1)C)C(O[C@@H]3CN(CC3)CC4=C(C([2H])=C(C([2H])=C4[2H])[2H])[2H])=O
Synonyms

Mepirodipine-d5; YM-09730-5-d5 Free base
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)