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Cat. No.: HY-164731

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Mal-PEG12-DOTA

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Mal-PEG12-DOTA is a RDC linker that can be used for the synthesis of RDC.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Pureté: 95.0%
Formule: C₄₉H₈₇N₇O₂₂
Masse moléculaire:1126.25

Stockage:

-20°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Mal-PEG12-DOTA Chemical Structure

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Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Mal-PEG12-DOTA is a RDC linker that can be used for the synthesis of RDC.

Voir tous les produits spécifiques à Isoform Radionuclide-Drug Conjugates (RDCs) :

In Vitro

Mal-PEG12-DOTA reacts with the targeted molecules (such as antibody fragments, peptides) that have been pre-reduced to free -SH groups at the Mal end to generate Target-Mal-PEG12-DOTA. Then, the DOTA end is incubated with radioactive metal isotopes (such as ⁶⁸GaCl₃) in a weakly acidic or near-neutral buffer. DOTA quantitatively chelates the metal, resulting in the final Target-PEG12-DOTA-⁶⁸Ga reagent.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Appearance Oil
Masse moléculaire 1126.25
Formule C₄₉H₈₇N₇O₂₂
Color Colorless to light yellow
SMILES

O=C(O)CN1CCN(CC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN2C(C=CC2=O)=O)=O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

-20°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)