Odanacatib (Standard)
Odanacatib (Standard) is the analytical standard of Odanacatib (HY-10042). This product is intended for research and analytical applications. Odanacatib (MK-0822) is a potent and selective inhibitor of cathepsin K, with an IC50 of 0.2 nM for human cathepsin K.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 603139-19-1
- Formule: C25H27F4N3O3S
- Masse moléculaire:525.56
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureté et documentation
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Help & FAQs
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HY-10042
OdanacatibCathepsin K Inhibitor -
HY-100229
AloxistatinCysteine Protease Inhibitor -
HY-100350
CA-074 methyl esterCathepsin B Inhibitor -
HY-15282
E-64Cysteine Peptidase Inhibitor -
HY-15533
LY 3000328Cathepsin S Inhibitor -
HY-D0843
N-EthylmaleimideCysteine Residues Modifier -
HY-B0496
PMSFCathepsin Inhibitor -
HY-103350
CA-074Cathepsin B Inhibitor -
HY-18234A
Leupeptin hemisulfateProtease Inhibitor -
HY-18236
MDL-28170Calpain Inhibitor -
HY-100223
CalpeptinCalpain Inhibitor -
HY-100227
E 64cCalpain Inhibitor
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 603139-19-1
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Masse moléculaire 525.56
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Formule C25H27F4N3O3S
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SMILES
N#CC1(NC([C@@H](N[C@H](C(F)(F)F)C2=CC=C(C3=CC=C(S(=O)(C)=O)C=C3)C=C2)CC(C)(F)C)=O)CC1
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Synonyms
MK-0822 (Standard)
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Jacques Yves Gauthier, et al. The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K. Bioorg Med Chem Lett. 2008 Feb 1;18(3):923-8. [Content Brief]
[2]. Leung P, et al. The effects of the cathepsin K inhibitor odanacatib on osteoclastic bone resorption and vesicular trafficking. Bone. 2011 Oct;49(4):623-635. [Content Brief]
[3]. Ng KW. Potential role of odanacatib in the treatment of osteoporosis. Clin Interv Aging. 2012;7:235-47. [Content Brief]
[4]. Yi C, et al. Inhibition of cathepsin K promotes osseointegration of titanium implants in ovariectomised rats. Sci Rep. 2017 Mar 17;7:44682. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Odanacatib (Standard) Related Classifications
HY-10042R Related Classifications
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