Undecanoic acid-d2
Undecanoic acid-d2 (Undecanoate-d2) is the deuterium labeled Undecanoic acid (HY-W004282). Undecanoic acid is a monocarboxylic acid with antifungal property. Undecanoic acid inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum.
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- CAS No.: 64118-43-0
- Formule: C11H20D2O2
- Masse moléculaire:188.30
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 64118-43-0
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Unlabeled Cas 112-37-8
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Masse moléculaire 188.30
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Formule C11H20D2O2
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SMILES
O=C(C([2H])([2H])CCCCCCCCC)O
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Synonyms
Undecanoate-d2; Hendecanoic acid-d2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Das SK, et al. Effect of undecanoic acid on phospholipid metabolism in Trichophyton rubrum. Sabouraudia. 1982 Dec;20(4):267-72. [Content Brief]
[3]. Das SK, et al. Effect of undecanoic acid on the production of exocellular lipolytic and keratinolytic enzymes by undecanoic acid-sensitive and -resistant strains of Trichophyton rubrum. Sabouraudia. 1982 Sep;20(3):179-84. [Content Brief]
[4]. Sathiyaseelan A, et al. Enhancing antifungal and biocompatible efficacy of undecanoic acid through incorporation with chitosan-based nanoemulsion. Int J Biol Macromol. 2024 May;267(Pt 1):131328. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)