1180924-34-8

EGFR/HER2/CDK9-IN-2 Chemical Structure
1180924-34-8

Chemical Structure

EGFR/HER2/CDK9-IN-2

  • CAS No.: 1180924-34-8
  • Formula:C23H20N4O5S2
  • Molecular Weight:496.56

IUPAC Name: 4-(2-(2-((4-nitrobenzyl)thio)-4-oxoquinazolin-3(4H)-yl)ethyl)benzenesulfonamide

InChIKey: WQEFYEUNVFDIII-UHFFFAOYSA-N

SMILES: O=S(C1=CC=C(CCN2C(SCC3=CC=C([N+]([O-])=O)C=C3)=NC4=C(C=CC=C4)C2=O)C=C1)(N)=O

Biological Activity: EGFR/HER2/CDK9-IN-2 (Compound 9) is a potent inhibitor of EGFR/HER2/CDK9 with IC50s of 145.35, 129.07, and 117.13 nM, respectively. EGFR/HER2/CDK9-IN-2 exhibits remarkable antitumor activity[1].

Cat. No. Product Name Purity Description Pricing
HY-147797 		EGFR/HER2/CDK9-IN-2 EGFR/HER2/CDK9-IN-2 (Compound 9) is a potent inhibitor of EGFR/HER2/CDK9 with IC50s of 145.35, 129.07, and 117.13 nM, respectively. EGFR/HER2/CDK9-IN-2 exhibits remarkable antitumor activity.
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