1251841-50-5
1251841-50-5
Chemical Structure
AZD6564
- CAS No.: 1251841-50-5
- Formula:C13H22N2O2
- Molecular Weight:238.33
IUPAC Name: 5-((2R,4S)-2-neopentylpiperidin-4-yl)isoxazol-3(2H)-one
InChIKey: ORLPPUHANSFJCS-VHSXEESVSA-N
SMILES: CC(C)(C)C[C@@H]1NCC[C@H](C(ON2)=CC2=O)C1
Biological Activity: AZD6564 is an orally active inhibitor for fibrinolysis through disruption of plasma kinase-fibrin interaction. AZD6564 dissolves human plasma clot with an IC50 of 0.44 μM. AZD6564 ameliorates hemorrhage in rats with EC50 of 1.62 μM, and exhibits good pharmacokinetic characteristics in rats[1].
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AZD6564 | AZD6564 is an orally active inhibitor for fibrinolysis through disruption of plasma kinase-fibrin interaction. AZD6564 dissolves human plasma clot with an IC50 of 0.44 μM. AZD6564 ameliorates hemorrhage in rats with EC50 of 1.62 μM, and exhibits good pharmacokinetic characteristics in rats. | |||||||||||||||||||||
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References
Keywords
