132565-33-4
132565-33-4
Chemical Structure
L-687908
- CAS No.: 132565-33-4
- Formula:C40H51N5O5
- Molecular Weight:681.86
IUPAC Name: tert-butyl ((2S,3S,5R,E)-5-(((2S,3S)-1-(((1H-benzo[d]imidazol-2-yl)methyl)amino)-3-methyl-1-oxopentan-2-yl)carbamoyl)-3-hydroxy-1,8-diphenyloct-7-en-2-yl)carbamate
InChIKey: XETIIHXJGVJJAT-FGXUATOGSA-N
SMILES: CC(C)(C)OC(N[C@@H](CC1=CC=CC=C1)[C@@H](O)C[C@@H](C/C=C/C2=CC=CC=C2)C(N[C@@H]([C@@H](C)CC)C(NCC3=NC4=CC=CC=C4N3)=O)=O)=O
Biological Activity: L-687908 is a HIV-1 protease inhibitor (CIC95: 12 nM)[1][2].
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L-687908 | L-687908 is a HIV-1 protease inhibitor (CIC95: 12 nM). | |||||||||||||||||||||
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References
- [1]. Kohl NE, et al. Expression of active human immunodeficiency virus type 1 protease by noninfectious chimeric virus particles. J Virol. 1991 Jun;65(6):3007-14. [Content Brief]
- [2]. Lin JH. Role of pharmacokinetics in the discovery and development of indinavir. Adv Drug Deliv Rev. 1999 Oct 18;39(1-3):33-49. [Content Brief]
Keywords
