1345715-43-6
Chemical Structure
Rev 2’-O-MOE-5MeU-5’-amidite
- CAS No.: 1345715-43-6
- Formula:C43H55N4O10P
- Molecular Weight:818.89
IUPAC Name: ((2R,3R,4R,5R)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)-4-(2-methoxyethoxy)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite
InChIKey: YXJWAPDGJHYLNH-KZQAAKLLSA-N
SMILES: CC(C)N(C(C)C)P(OC[C@H]1O[C@@H](N2C(NC(C(C)=C2)=O)=O)[C@H](OCCOC)[C@@H]1OC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)OCCC#N
Biological Activity: Rev 2’-O-MOE-5MeU-5’-amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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Rev 2’-O-MOE-5MeU-5’-amidite | Rev 2’-O-MOE-5MeU-5’-amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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Keywords
