2072145-46-9
2072145-46-9
Chemical Structure
9-(2’-O-Acetyl-5’-O-benzoyl-3’-O-methyl-beta-D-ribofuranosyl)-6-chloropurine
- CAS No.: 2072145-46-9
- Formula:C20H19ClN4O6
- Molecular Weight:446.84
IUPAC Name: ((2R,3R,4R,5R)-4-acetoxy-5-(6-chloro-9H-purin-9-yl)-3-methoxytetrahydrofuran-2-yl)methyl benzoate
InChIKey: JMHJIDXOJPMSAL-NVQRDWNXSA-N
SMILES: CO[C@H]1[C@@H](OC(C)=O)[C@H](N(C=N2)C3=C2C(Cl)=NC=N3)O[C@@H]1COC(C4=CC=CC=C4)=O
Biological Activity: 9-(2’-O-Acetyl-5’-O-benzoyl-3’-O-methyl-beta-D-ribofuranosyl)-6-chloropurine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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9-(2’-O-Acetyl-5’-O-benzoyl-3’-O-methyl-beta-D-ribofuranosyl)-6-chloropurine | 9-(2’-O-Acetyl-5’-O-benzoyl-3’-O-methyl-beta-D-ribofuranosyl)-6-chloropurine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
