2156651-18-0
Chemical Structure
PD-1/PD-L1-IN-19
- CAS No.: 2156651-18-0
- Formula:C32H29BrClN3O3
- Molecular Weight:618.95
IUPAC Name: N-(2-((4-((2-bromo-[1,1'-biphenyl]-3-yl)methoxy)-5-chloro-2-((3-cyanobenzyl)oxy)benzyl)amino)ethyl)acetamide
InChIKey: OULXBALIHGTTTF-UHFFFAOYSA-N
SMILES: N#CC1=CC=CC(COC2=CC(OCC3=CC=CC(C4=CC=CC=C4)=C3Br)=C(C=C2CNCCNC(C)=O)Cl)=C1
Biological Activity: PD-1/PD-L1-IN-19 (Example 22) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-19 blocks PD-1/PD-L1 with the IC50 of 62.3 nM. PD-1/PD-L1-IN-19 can be used for the research of cancers, infectious diseases and autoimmune diseases[1].
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PD-1/PD-L1-IN-19 | PD-1/PD-L1-IN-19 (Example 22) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-19 blocks PD-1/PD-L1 with the IC50 of 62.3 nM. PD-1/PD-L1-IN-19 can be used for the research of cancers, infectious diseases and autoimmune diseases. | |||||||||||||||||||||
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Keywords
