2196448-47-0
2196448-47-0
Chemical Structure
EN1441
- CAS No.: 2196448-47-0
- Formula:C13H13ClN2O2
- Molecular Weight:264.71
SMILES: ClC1=CC2=C(NC(C(N2C(C=C)=O)(C)C)=O)C=C1
Biological Activity: EN1441 is a covalent degrader targeting the androgen receptor (AR) with an EC50 value of 4.2 μM and its truncated variant AR-V7. EN1441 selectively and potently degrades both AR and AR-V7 in androgen-independent prostate cancer cells. EN1441 is promising for research of androgen-independent prostate cancers[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
EN1441 | 99.67% | EN1441 is a covalent degrader targeting the androgen receptor (AR) with an EC50 value of 4.2 μM and its truncated variant AR-V7. EN1441 selectively and potently degrades both AR and AR-V7 in androgen-independent prostate cancer cells. EN1441 is promising for research of androgen-independent prostate cancers. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
