2242615-97-8
2242615-97-8
Chemical Structure
Chloroguanabenz acetate
Synonym(s): GAh acetate
- CAS No.: 2242615-97-8
- Formula:C10H11Cl3N4O2
- Molecular Weight:325.58
SMILES: ClC1=C(C(Cl)=CC=C1Cl)/C=N/NC(N)=N.OC(C)=O
Biological Activity: Chloroguanabenz (acetate) is an antiprion agent and a derivative of the α2-adrenergic receptor agonist guanabenz. Chloroguanabenz (acetate) can inhibit the formation of prion in yeast and mammalian in vitro assays. Chloroguanabenz (acetate) can reduce the levels of truncated Huntingtin derivative Htt48 in HEK293T cells. Chloroguanabenz (acetate) can be studied in research on Huntington’s disease[1][2].
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Chloroguanabenz acetate | Chloroguanabenz (acetate) is an antiprion agent and a derivative of the α2-adrenergic receptor agonist guanabenz. Chloroguanabenz (acetate) can inhibit the formation of prion in yeast and mammalian in vitro assays. Chloroguanabenz (acetate) can reduce the levels of truncated Huntingtin derivative Htt48 in HEK293T cells. Chloroguanabenz (acetate) can be studied in research on Huntington’s disease. | |||||||||||||||||||||
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References
Keywords
