2306389-04-6
Chemical Structure
(S,R,S)-AHPC-C7-amine
Synonym(s): VH032-C7-amine
- CAS No.: 2306389-04-6
- Formula:C30H45N5O4S
- Molecular Weight:571.77
IUPAC Name: (2S,4R)-1-((S)-2-(8-aminooctanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
InChIKey: KHXMEYUTLVQWBB-ONBPZOJHSA-N
SMILES: O=C([C@H]1N(C([C@@H](NC(CCCCCCCN)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2
Biological Activity: (S,R,S)-AHPC-C7-amine (VH032-C7-amine) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader[1].
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(S,R,S)-AHPC-C7-amine | (S,R,S)-AHPC-C7-amine (VH032-C7-amine) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader. | |||||||||||||||||||||
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Keywords